Personal Page of Jorma Jyrkkanen, Composer, Author, Researcher

Abstract

Lysol is a disinfectant designed for use on surfaces and contains phenol, a protoplasmic poison. Poisoning from Lysol can occur through oral ingestion, skin contact, inhalation, and other means. Phenol is mainly metabolized by the kidneys, and after absorption, it causes widespread capillary damage and clotting in superficial blood vessels. This results in urine that is scanty with traces of albumin, and microscopically, blood and calcium oxalate crystals are observed. The urine turns olive green or brown on standing, a phenomenon called carboluria. Studies by J. Jyrkkanen 2020 on antibiotic impacts on mitochondria showed that ROS damage and ruptures of mitochondria resulted in pathology leading to loss of oxidative phosphorylation, likelihood of increase in cancers favorite metabolism aerobic glycolysis, suppression of the p53 DNA repair gene, cardiovascular ailments and immune dysfunction. The similarity of damage reported here by google AI suggest a similar pathology for Lysol type antibiotic cleaners. Otherwise damaged mitochondria induced effects have been observed also for some common pesticides, and mRNA vaccine. The problem arises from the fact that Lysol is an antibiotic that kills bacteria and mitochondria are a highly modified essential symbiotic derivative of an ancient bacteria.

Characteristics	Values
Sensation	Constriction around the throat, burning pain from the mouth to the epigastrium
Taste	Sour and acidic
Urine	Scanty, with traces of albumin
Microscopic Observations	Blood and calcium oxalate crystals
Other Observations	Burns on the face and skin, mucosa of the mouth, tongue, pharynx, and esophagus may be bleached
Phenol Metabolism	Converted into hydroquinone and pyrocatechol, then excreted in urine
Urine Color	Olive green or brown on standing (carboluria)

Impacts on Mitochondria

The active ingredient benzalkonium chloride reveal a pattern of cellular toxicity mediated by mitochondrial damage.

Disruption of Energy Production

QACs which are commonly used in antimicrobial products, have been shown to inhibit mitochondrial respiration specifically at Complex I of the electron transport chain, leading to a decrease in cellular energy (ATP)

Structural Damage or Fragmentation

Exposure to these compounds causes structural disruption, resulting in mitochondrial fragmentation and changes in mitochondrial membrane potential

Induction of Oxidative Stress

Similar to other chemical sanitizers, these compounds can induce the generation of reactive oxygen species (ROS) within the mitochondria, causing further impairment.

Initiation of Apoptosis

Mitochondrial dysfunction caused by these surfactants can trigger the mitochondrial pathway of apoptosis or programmed cell death

Compounds with Documented Mitochondrial Toxicity

Quaternary Ammonium Compounds (QAC’s/BAC’s) induce mitochondrial dysfunction in epithelial cells

Cetylpyridinium Chloride (CPC) CPC causes severe nanostructural disruption, reduces ATP production, and acts as a mitochondrial inhibitor.

Ammonium Hydroxide a caustic compound present in some cleaners can cause severe irritation and potential cellular disruption.

CONCLUSION

These disinfectants can cause significant mitochondrial dysfunction in mammalian cells leading to significant morbidity and mortality. While disinfectant effect may reduce exposure to pathogenic microbes in the short term the harm to beneficial endogenous mitochondria may cause health issues in the long term.

References

Jyrkkanen jccm-aid1104

Jyrkkanen J. Antibiotic
induced changes to mitochondria result in
potential contributions to carcinogenesis, heart
pathologies, other medical conditions and
ecosystem risks. J Cardiol Cardiovasc Med.
2020; 5: 163-171